This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.
However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
Read More
7
Nattokinase affects hemostatic factors
The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects.
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.
We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.
In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
Read More
Most Useful Reviews
9
Thinned blood
394 people found this helpful
My father has had thick blood due to high cholesterol and blood clots for years. After developing diabetes post-Covid, he faced more challenges. I ordered this highly rated Nattokinase supplement for him, and within a month, he noticed his blood becoming much thinner. His blood pressure is also normalising after a long struggle with it. He is extremely pleased with the results and highly recommends this product.
Read More
9
Cardiovascular support
190 people found this helpful
Nattokinase is an excellent enzyme for dissolving blood clots and is widely recognised in various countries. It holds great promise for thrombolytic therapy and supports overall cardiovascular health. I am pleased with the quality and effectiveness of "Doctor's Best" Nattokinase; it has exceeded my expectations.
Read More
9
Pressure regulation
188 people found this helpful
I use nattokinase to improve my blood fluidity, addressing my thick blood caused by high cholesterol, which elevates my pressure and clot risk. I take it in the evening and on an empty stomach in the morning. Since using it regularly, I have forgotten about my blood pressure issues.
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.
However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
Read More
7
Nattokinase affects hemostatic factors
The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects.
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.
We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.
In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
Read More
User Reviews
USERS' SCORE
Good
Based on 159 Reviews
8.1
All Reviews
Positive Reviews
Negative Reviews
9
Thinned blood
394 people found this helpful
My father has had thick blood due to high cholesterol and blood clots for years. After developing diabetes post-Covid, he faced more challenges. I ordered this highly rated Nattokinase supplement for him, and within a month, he noticed his blood becoming much thinner. His blood pressure is also normalising after a long struggle with it. He is extremely pleased with the results and highly recommends this product.
Read More
9
Cardiovascular support
190 people found this helpful
Nattokinase is an excellent enzyme for dissolving blood clots and is widely recognised in various countries. It holds great promise for thrombolytic therapy and supports overall cardiovascular health. I am pleased with the quality and effectiveness of "Doctor's Best" Nattokinase; it has exceeded my expectations.
Read More
9
Pressure regulation
188 people found this helpful
I use nattokinase to improve my blood fluidity, addressing my thick blood caused by high cholesterol, which elevates my pressure and clot risk. I take it in the evening and on an empty stomach in the morning. Since using it regularly, I have forgotten about my blood pressure issues.
Read More
9
Promotes heart health
94 people found this helpful
Nattokinase is vital for blood flow, boasting high fibrinolytic activity and beneficial effects such as reducing high cholesterol and promoting heart health. It also helps alleviate varicose veins and headaches.
Read More
9
Normalises blood pressure
86 people found this helpful
My father has had thick blood due to high cholesterol and developed diabetes post-COVID. After trying various blood thinners, this nattokinase supplement worked excellently, normalising his blood pressure efficiently within a month.
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Nattokinase is an enzyme extracted from a traditional Japanese food called natto, which is made from fermented soybeans. This enzyme is thought to have potential health benefits, primarily for cardiovascular health. Nattokinase is believed to support the breakdown of fibrin in the blood, which can help improve circulation and reduce the risk of blood clot formation. As a dietary supplement, it is often marketed for its possible ability to promote healthy blood flow and cardiovascular function.
While some studies suggest that nattokinase may help reduce blood pressure and enhance overall heart health, research is still ongoing. As with any supplement, it is essential to consult with a healthcare professional before adding nattokinase to your regimen, especially if you are on blood-thinning medications or have underlying health conditions. Overall, while nattokinase might offer some intriguing health benefits, more comprehensive studies are needed to fully understand its efficacy and safety profile.
Based on user reviews, it appears that many individuals may begin to notice results from taking Nattokinase for high cholesterol within a month. For instance, one user noted significant improvements in their father's blood viscosity and normalization of blood pressure in just 30 days of use Read Review. Similarly, another reviewer reported a marked decrease in their blood pressure after four weeks of daily intake of Nattokinase, indicating that it acted effectively as an alternative to prescription medications Read Review.
Additionally, those who have used Nattokinase highlight its cumulative benefits over time, with some participants in the reviews expressing that consistent use has led to ongoing improvements in their cardiovascular health and cholesterol levels Read Review. Overall, while the initial effects may be seen within a month, users recommend considering a longer-term approach for optimal results.
Nattokinase supplements may offer some benefits for managing cholesterol levels, according to recent scientific studies. One clinical trial involving 113 participants indicated that nattokinase monascus supplements resulted in significant reductions in total cholesterol and LDL cholesterol over a 120-day period compared to a placebo group. However, it’s worth noting that other lipid markers, such as triglycerides and HDL cholesterol, did not show notable improvements, limiting the overall effectiveness of the supplement in cholesterol management [1].
Another study of 100 participants further explored the effects of nattokinase on high cholesterol, finding no significant changes in overall cholesterol levels, despite some improvements in hemostatic factors measured during the trial [2]. This reveals that while nattokinase has demonstrated potential in lowering certain types of cholesterol, the overall evidence suggests it may not be a comprehensive solution for cholesterol management. As with any supplement, it’s essential to consider individual health situations and consult healthcare providers before starting new treatments.
Based on user reviews, many individuals report notable improvements in their symptoms after taking Nattokinase. Users have shared positive experiences in managing conditions such as high blood pressure and cholesterol levels. For instance, one user highlighted significant normalization of their father's blood pressure and improved blood viscosity within just a month of use Read Review. Another reviewer experienced a remarkable 50-point drop in their blood pressure after trying Nattokinase and noted the absence of side effects Read Review. Consistent use reportedly leads to ongoing benefits, as some users assert that it has become a long-term solution, contributing to improved cardiovascular health and symptoms related to conditions like diabetes and hypercholesterolemia Read Review.
Moreover, users emphasize Nattokinase's effectiveness in dissolving blood clots and supporting overall vascular health, with one account expressing amazement at the speed with which a significant blood clot resolved Read Review. Reviews consistently suggest that this supplement not only aids in the management of blood pressure and cholesterol issues but also enhances overall well-being, making it an attractive alternative for those seeking non-prescription solutions. However, it is important to note that individual results can vary, and what works for one person may not necessarily work for another.
Users have reported positive experiences when combining Nattokinase with other supplements for managing high cholesterol and blood pressure. Specifically, one review highlighted that taking Nattokinase alongside serrapeptase resulted in a substantial drop in blood pressure over a four-week period, leading the user to successfully discontinue prescription medication Read Review. This suggests that a synergistic effect may exist between these two supplements, benefiting those looking for natural alternatives to traditional medications.
Moreover, users emphasize the cumulative benefits of consistent Nattokinase use alongside possible dietary or lifestyle changes. One user noted that after integrating Nattokinase into their regimen, significant improvements in cholesterol levels were observed in just a month, affirming its ability to complement other health protocols effectively Read Review. This trend extends to various conditions, with many users pursuing a holistic approach by incorporating multiple supplements to enhance cardiovascular health and overall well-being.
Based on user reviews, the right dosage of Nattokinase for treating high cholesterol appears to vary, but many users report positive results with regular daily intake. For example, one user mentioned they take Nattokinase daily, both in the evening and on an empty stomach in the morning, which has helped alleviate their blood pressure issues and improve blood fluidity Read Review. Another user stated they have been using it for around a month, which yielded promising blood work results Read Review.
Users also emphasize the importance of consistency with Nattokinase for optimal benefits, as some reported significant improvements in blood tests after just a month of regular use Read Review. Although there isn't a universally prescribed dosage mentioned in the reviews, many users suggest daily consumption is key to managing cholesterol levels effectively while also improving cardiovascular health Read Review.
9
Thinned blood
394 people found this helpful
My father has had thick blood due to high cholesterol and blood clots for years. After developing diabetes post-Covid, he faced more challenges. I ordered this highly rated Nattokinase supplement for him, and within a month, he noticed his blood becoming much thinner. His blood pressure is also normalising after a long struggle with it. He is extremely pleased with the results and highly recommends this product.
9
Lowered blood pressure
9 people found this helpful
Taking Nattokinase alongside serrapeptase reduced my blood pressure dramatically after years of being high. I stopped my prescription medication four weeks ago, and my blood pressure is now normal, thanks to this supplement.
9
Family health boost
24 people found this helpful
Nattokinase has been a long-term investment in our health, particularly for addressing high cholesterol. The gentle blood-thinning effects help prevent the formation of clots and alleviate symptoms of migraines. We have noticed its cumulative impact, especially for my elderly parents, who now use it regularly. By prioritising our vascular health, we aim to diminish the risk of strokes or heart attacks in our family.
9
Lowered blood pressure
8 people found this helpful
I was hesitant to take prescription drugs for high blood pressure. However, after trying Nattokinase, I was amazed by the 50-point drop! Remarkably, there were no side effects at all.
9
Quick results
17 people found this helpful
Nattokinase has proven incredible for me; it dissolved a significant blood clot in my leg within days, astonishing my doctor. He was amazed that such clots typically take weeks to resolve. I've been taking this in high doses and intend to continue its use for better cardiovascular health.
9
Significant health improvements
9 people found this helpful
After researching Nattokinase for my parents, who suffer from high cholesterol and blood pressure, we noticed significant improvements after just a month of use. Their test results returned to normal levels, making me very satisfied with the outcome.
9
Pressure regulation
188 people found this helpful
I use nattokinase to improve my blood fluidity, addressing my thick blood caused by high cholesterol, which elevates my pressure and clot risk. I take it in the evening and on an empty stomach in the morning. Since using it regularly, I have forgotten about my blood pressure issues.
9
Positive blood results
7 people found this helpful
Nattokinase has worked wonders for me as an alternative to statins for my high cholesterol. I’ve been taking it for a month, and my blood work results were promising. The easy-to-swallow capsules are taken on an empty stomach.
9
Aspirin alternative
47 people found this helpful
Nattokinase is a potent fibrinolytic enzyme, absorbed into the bloodstream to enhance fluidity. It’s recognised for its effectiveness in preventing and treating cardiovascular issues. It comes from Natto, a specific strain of bacteria enhances its benefits. Regular consumption of Nattokinase could reduce blood viscosity and is a safer alternative to aspirin, with no side effects detected over 20 years.
8
Nattokinase shows mixed cholesterol benefits
The Effect of Nattokinase-Monascus Supplements on Dyslipidemia: A Four-Month Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
This study examined whether nattokinase monascus supplements could effectively lower cholesterol levels in people facing dyslipidemia. In a randomized trial with 113 participants, we noted significant reductions in total cholesterol, LDL cholesterol, and similar lipid markers after 120 days of using the supplements compared to a placebo.
However, we didn't see any notable improvements in triglycerides, HDL cholesterol, or carotid intima-media thickness. Importantly, participants experienced no major side effects from the treatment. Overall, while nattokinase supplements showed promise for some cholesterol levels, they did not deliver significant changes in all examined lipid factors.
7
Nattokinase affects hemostatic factors
The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects.
We explored how nattokinase supplementation affects cholesterol levels and related hemostatic factors in individuals with high cholesterol. In a study with 100 participants, we divided them into nattokinase and placebo groups to monitor their responses over eight weeks.
We found that while there were no significant differences in initial measurements, those taking nattokinase showed notable increases in collagen-epinephrine closure time and activated partial thromboplastin time. However, these results indicate effects on hemostatic factors rather than a direct benefit to cholesterol levels.
In summary, while nattokinase appeared effective at influencing certain blood measures, it did not significantly improve overall cholesterol management.
References
Liu X, Zeng X, Mahe J, Guo K, He P, et al. The Effect of Nattokinase-Monascus Supplements on Dyslipidemia: A Four-Month Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2023;15. doi:10.3390/nu15194239
Yoo HJ, Kim M, Kim M, Lee A, Jin C, et al. The effects of nattokinase supplementation on collagen-epinephrine closure time, prothrombin time and activated partial thromboplastin time in nondiabetic and hypercholesterolemic subjects. Food Funct. 2019;10:2888. doi:10.1039/c8fo02324g